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Sartorius A-14C-1US Centrisart A-14C Refrigerated Microcentrifuge and YCSR-A1C Rotor

Sartorius A-14C-1US Centrisart A-14C Refrigerated Microcentrifuge and YCSR-A1C Rotor

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  • $5,300.00
  • Save $160


Model: A-14C-1US
Condition:

Brand new in its original packaging

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Centrisart A-14C Refrigerated Microcentrifuge and YCSR-A1C Rotor

Note: For all International Orders, the buyer will be solely responsible for the customs clearance, duty, and taxes imposed on the package.

High performance, space-saving refrigerated microcentrifuge, ideally suited for applications in molecular biology, from nucleic acid isolation to cell pelletization.

  • Optimal combination - Rotors for Sartorius VivaSpin units
  • Sample protection - Reliable sample cooling to 4 degree C at max.
  • Compact - Very small footprint (27 x 24 cm)
  • Volume | Capacity: 24 x 2 mL | 48 mL

The Centrisart A-14C microcentrifuge is extremely compact and saves space. The powerful centrifuge provides a maximum speed of 15,000 rpm and a capacity of 24 x 2 mL. The A-14C microcentrifuge is ideal for nucleic acid isolation and purification using centrifuge columns and concentrating biological samples using the Sartorius Vivaspin 500 units. The special YCSR-A1C rotor made to measure for the Vivaspin 500 accepts sample concentration by ultrafiltration, for example, of antibody solutions, desalination or buffer exchange and removal of contaminants with low or very large molecular weights. In addition, with the A-14C microcentrifuge, cells or particles in small volumes can be sedimented. The unit is equipped with large control buttons and an easy-to-read screen.

Thanks to its small size, the Centrisart A-14C microcentrifuge fits on any laboratory bench. The low height and the motorized lock cap ensure convenient sample loading and removal. With a gentle push, the lid closes automatically and, upon completion, it is unlocked with just a touch of a button. With just one finger, the lid can be opened and held in place by a spring-loaded mechanism, which prevents it from falling. The lid's electronic lock prevents the lid from accidentally opening during operation, offering greater protection to the user.

The Centrisart A-14C microcentrifuge offers exceptional product quality and meets the highest safety requirements. For example, the high quality is reflected by the low level noise of a maximum of 53 dB and the chemical resistance of the materials used. The quick-locking rotor cover prevents the spread of aerosols and both the rotor chamber and the rotors are easy to clean. For temperature sensitive samples, the Centrisart A-14C microcentrifuge active cooling option can be used. The pre-cooling function helps to cool the unit quickly to the set temperature and, even at maximum speed, the model A-14C guarantees reliable sample cooling down to 4 degree C.

  • Splash-proof keyboard with clear screen
  • Keys with tactile feedback
  • Glove operation possible
  • Automatic speed conversion and RCF
  • Speed ??200-15,000 min-1, adjustable in increments of 100 min-1
  • Gravitational fields (RCF) max. 16,602 g, adjustable in 10 xg increments
  • 10 s time - 99 min, adjustable in 1 s steps, short run, continuous run
  • Memory for 10 programs
  • Temperature range from -10 to 40 degree C, adjustable in steps of 1 degree C
  • Reliable sample cooling to 4 degree C, even at max rpm.
  • Rapid pre-cooling mode
  • Optional soft start or soft stop
  • Last configuration memory
  • Rotor chamber with air-driven cooling
  • Maintenance-free engine
  • Motorized lock cover, automatic cover release
  • Emergency cover lock release
  • Ergonomic operation of the lid with one finger
  • High chemical resistance
  • Pleasantly quiet operation

Optimized small scale SUTFF processing
The Allegro CM150 Auto TMP control is a single-use tangential flow filtration (SUTFF) semi-automated system designed for pilot or small scale process ultrafiltration and diafiltration (UF/DF) applications at 2-20 L batch volumes.

The system layout is optimized for a low minimum recirculation loop, to ensure final target volumes can be achieved and provide excellent product recovery.

The programmable logic controller (PLC) based control system ensures easy operation and monitoring of UF applications, constant volume diafiltration, and provides real-time trending and data logging capabilities.

  • Designed for ease of use
  • Single-use sensors - Pressure, flow, conductivity, temperature, ultraviolet (UV)
  • Low feed / retentate volume ~100 mL
  • Excellent product recovery
  • 0.1 - 0.4 m2 cassette area

System Functionality
Scalability of performance is critical in developing tangential flow filtration (TFF) processes. The Allegro CM150 system is designed for use in small scale good manufacturing practice (GMP) manufacture and for process development activities, to generate scalable data. Continuity of single-use component choice and design approach across our system range provides reliable scale up from Allegro CM150 system to the larger scale Allegro SUTFF systems.

The system offers the flexibility needed for single-use processing. The base system can run with just pressure and flow sensors or utilize the additional optional sensors for conductivity, temperature and UV, depending on the process requirements. The base system accommodates this flexibility, and base systems can be upgraded later if additional features are needed for new projects.

Flexibility

  • Single-use sensors
  • Pressure: Feed and retentate
  • Flow: Retentate
  • Temperature: Feed (optional)
  • Conductivity: Permeate (optional)
  • UV: Permeate (optional)
  • Transmembrane pressure (TMP) control
  • Manual pinch valve
  • Automatic pinch valve
  • Tray for retentate biocontainer assemblies: 5 L and 10 L
  • Adjustable tray comes to lower position for easy installation of the biocontainer assembly, and is then moved to the upper position for processing
  • Accessory biocontainers and bespoke trolley

Control System
The Allegro CM150 offers automatic transmembrane pressure as well as retentate biocontainer weight control. The diafiltration pump can be set to automatically control the pump speed to maintain a constant mass in the retentate biocontainer according to the defined input weight.

Automated TMP Control Valve
The integration of a Transmembrane pressure (TMP) control valve offers the following benefits:

  • Improved process control and reproducibility.
  • Prevent high protein wall concentrations (polarization) or fouling.
  • Minimized human error due to manual operation.

Automated Weight Control:

The diafiltration pump speed can automatically be controlled, to maintain a constant retentate biocontainer weight. This can be used for Diafiltration as well as for Product fed batch during concentration.

All process values are shown in the piping and installation diagram (P&ID) based operator interface. The main screen indicates all process signals as well as system/ component status.

The header bar clearly indicates the current user logged into the system, and provides the operator with navigation buttons to other areas of the control system.

A wireless link to a tablet, smartphone or PC enables remote viewing of the system screen and wireless transfer of data files.

The control software is designed for flexible and user friendly control of tangential flow filtration processes, providing the following key features:

  • P&ID based user interface with dynamic flow path
  • Retentate biocontainer weight controller
  • Transmembrane pressure controller
  • Full security access to configuration settings screens
  • Real-time trending
  • Data logging with data transfer in comma separated value (CSV) or line-delimited format
  • 3 level user login, user administration and password control

Specification:

  • Height with open lid: 404 mm
  • Dimensions (WxDxH): 273 x 515 x 236 mm
  • Cooling: Sim
  • Cooling Programs: Precooling, guaranteed 4 degree C at max. speed
  • Display: Concise display
  • Lid: Inspection window for independent speed measurement
  • Maximum number of programs: 10
  • Rotor Detection: No
  • Timer: 0:00:10 - 99:99:59 hh:mm:ss, short run & continuous run
  • Maximm Volume Capacity: 24 x 2 mL
  • Maximum speed: 15,000 RPM
  • Current consumption: 230 W
  • Line tension: 100 - 120 V, 50 - 60 Hz [US]
  • Rotor Type: Fixed angle rotors
  • Acceleration curves: 2
  • Deceleration curves: 2
  • Maximum Gravitational Force: 16,602 x g
  • Temperature range: -10 degree C - +40 degree C
  • Noise level at max. (approx.): 53 dB
  • Minimum effective speed: 200 RPM
  • Weight: 19 kg

Brochure
Centrisart Centrifuges - The Ultimate Speed. Maximum Reliability.

Data Sheet
Centrisart A-14C - Micro-Centrifuge

User Manual
Centrisart A-14C

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